BioFlyte is a venture-backed biodefense company commercializing a revolutionary new class of fieldable biological threat collection, detection, and identification solutions. The U.S. Department of Defense is funding the development of BioFlyte’s miniaturized, low-cost, low-power mass spectrometer technology for the detection and identification of aerosolized bio-threats in near real-time. The firm’s current focus is infrastructure protection and emergency response. The BioFlyte™ z200 bioaerosol identifier is a combination collector/detector/identifier system that uses matrix-assisted laser desorption and ionization (MALDI) mass spectrometry to acquire the mass spectrum profile from the collected aerosol sample. The z200 provides a presumptive identification in less than five minutes from receipt of trigger signal or can be triggered by an internal Fluorescent APS bioaerosol detector, an external trigger sensor, or from a sensor network. The sample is only partially desorbed by the MALDI TOF MS measurement, and the remaining sample is retained for subsequent laboratory analysis. The z200 enables effective and sustainable “detect-to-protect” architectures for critical infrastructure. The BioCapture® z750 was created to provide CBRN Defense Forces and Emergency Response Teams with a high-performance handheld bioaerosol sampler. It is a direct replacement and an upgrade to the BioCapture 650. The z750 handheld collector is designed around a proven Dry Filter Unit (DFU) technology that has been in use worldwide for decades. The advanced filter design incorporated into the z750 has extensively validated sample extraction protocols and is compatible with PCR, immunoassay, and fieldable mass spec instruments, as well as analytical methods associated with laboratory confirmation. The FLAPS z100 is a bioaerosol trigger sensor incorporates a fluorescence measurement using a 405nm laser, and further includes scattering and aerodynamic particle sizing. This product is being launched in Q22021.